High-dose etoposide treatment for CNS involvement in a patient with primary non-Hodgkin's lymphoma of the breast.

@article{Kohara1997HighdoseET,
  title={High-dose etoposide treatment for CNS involvement in a patient with primary non-Hodgkin's lymphoma of the breast.},
  author={Hiroyuki Kohara and Hiroshi Ueoka and Mitsuhisa Tabata and Katsuji Shinagawa and Kazuki Hayashi and M. D. N. Harada},
  journal={Internal medicine},
  year={1997},
  volume={36 10},
  pages={738-41}
}
A 46-year-old man was referred to us for treatment of non-Hodgkin's lymphoma (NHL; diffuse large immunoblastic B cell type), which had initially developed in the breast. He was treated with five courses of chemotherapy with CHOP (cyclophosphamide, adriamycin, vincristine, and prednisolone) and achieved a complete response. One year later, he noticed a gait disturbance. Magnetic resonance imaging (MRI) of the brain showed multiple nodules. A few abnormal cells were found in the cerebrospinal… CONTINUE READING