High-dose chemotherapy with carboplatin, etoposide and cyclophosphamide followed by a haematopoietic stem cell rescue in patients with high-risk retinoblastoma: a SFOP and SFGM study.

@article{Namouni1997HighdoseCW,
  title={High-dose chemotherapy with carboplatin, etoposide and cyclophosphamide followed by a haematopoietic stem cell rescue in patients with high-risk retinoblastoma: a SFOP and SFGM study.},
  author={Fouad Namouni and François Doz and Marie Laure Tanguy and Erica Quintana and Jean Marie Michon and H{\'e}l{\`e}ne D Pacquement and Eric Bouffet and Jean Claude Gentet and Dominique Plantaz and Patrick Lutz and J P Vannier and Pierre Validire and Sylvia Neuenschwander and Laurence Desjardins and Jean Michel Zucker},
  journal={European journal of cancer},
  year={1997},
  volume={33 14},
  pages={2368-75}
}
This study investigates the role of high-dose chemotherapy with haematopoietic stem cell rescue as consolidation treatment in high-risk retinoblastoma (extraocular disease at diagnosis or relapse or invasion of cut end of optic nerve). 25 patients received high-dose chemotherapy including carboplatin (250 mg/m2/day from day 1 to day 5 for the 6 first patients and 350 mg/m2/day from day 1 to day 5 for the other patients), etoposide (350 mg/m2/day from day 1 to day 5) and cyclophosphamide (1.6 g… CONTINUE READING

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