High-dose adjuvant radiotherapy after radical prostatectomy with or without androgen deprivation therapy.

@article{Ost2012HighdoseAR,
  title={High-dose adjuvant radiotherapy after radical prostatectomy with or without androgen deprivation therapy.},
  author={Piet Ost and Cesare Cozzarini and Gert De Meerleer and Claudio Fiorino and Bruno De Potter and Alberto Briganti and Evi V T Nagler and Francesco Montorsi and Val{\'e}rie Fonteyne and Nadia Gisella Di Muzio},
  journal={International journal of radiation oncology, biology, physics},
  year={2012},
  volume={83 3},
  pages={960-5}
}
PURPOSE To retrospectively evaluate the outcome and toxicity in patients receiving high-dose (>69 Gy) adjuvant radiotherapy (HD-ART) and the impact of androgen deprivation therapy (ADT). METHODS AND MATERIALS Between 1999 and 2008, 225 node-negative patients were referred for HD-ART with or without ADT to two large academic institutions. Indications for HD-ART were extracapsular extension, seminal vesicle invasion (SVI), and/or positive surgical margins at radical prostatectomy (RP). A dose… CONTINUE READING
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