High-dose Oral Pyridoxine for Treatment of Pediatric Recurrent Intractable Seizures

@inproceedings{AKHOONDIAN2012HighdoseOP,
  title={High-dose Oral Pyridoxine for Treatment of Pediatric Recurrent Intractable Seizures},
  author={JAVAD AKHOONDIAN and Saeed Talebi},
  year={2012}
}
Intractable epilepsy is a common clinical problem in pediatrics and approxi­ mately 13% of children with epilepsy experience intractable seizures. To deter­ mine the efficacy of pyridoxine in treating seizures, 30 infants and children with recurrent seizures were enrolled in the present study. All of them were treated with high-dose oral pyridoxine (40 mg/kg/day), as an adjunct to antiepileptic drugs. Clinical efficacy criteria were based on the daily frequency of seizures after therapy was… CONTINUE READING

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