High-dose GH treatment limited to the prepubertal period in young children with idiopathic short stature does not increase adult height.

Abstract

OBJECTIVE To assess the long-term effect of prepubertal high-dose GH treatment on growth in children with idiopathic short stature (ISS). DESIGN AND METHODS Forty children with no signs of puberty, age at start 4-8 years (girls) or 4-10 years (boys), height SDS <-2.0 SDS, and birth length >-2.0 SDS, were randomly allocated to receive GH at a dose of 2 mg… (More)
DOI: 10.1530/EJE-09-0880

Topics

Cite this paper

@article{Gool2010HighdoseGT, title={High-dose GH treatment limited to the prepubertal period in young children with idiopathic short stature does not increase adult height.}, author={Sandy A. van Gool and Gerdine A. Kamp and Roelof J H Odink and Sabine M P F de Muinck Keizer-Schrama and Henri{\"{e}tte A. Delemarre-van de Waal and Wilma Oostdijk and J. M. Wit}, journal={European journal of endocrinology}, year={2010}, volume={162 4}, pages={653-60} }