High dose 1,25(OH)2D3 inhibits osteoblast mineralization in vitro.

Abstract

Vitamin D is essential for optimal calcium absorption needed for maintaining normal bone mineral density (BMD). Consequently, vitamin D-deficiency leads to poorly mineralized bone with diminished strength and load bearing capacity. Surprisingly, several animal and clinical studies have identified suppressive effects of… (More)
DOI: 10.3892/ijmm.2012.900

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