High diversity of HHV-8 molecular subtypes in the Amazon region of Brazil: evidence of an ancient human infection.

@article{Ishak2007HighDO,
  title={High diversity of HHV-8 molecular subtypes in the Amazon region of Brazil: evidence of an ancient human infection.},
  author={Marlu{\'i}sa de Oliveira Guimar{\~a}es Ishak and Rosimar Neris Martins and Paula Renata Lima Machado and Lia Lobato Batista de Souza and Luiz Fernando Almeida Machado and V{\^a}nia Nakauth Azevedo and Harutaka Katano and Tetsutaro Sata and Hideki Hasegawa and Antonio Carlos Ros{\'a}rio Vallinoto and Ricardo Ishak},
  journal={Journal of medical virology},
  year={2007},
  volume={79 10},
  pages={1537-44}
}
The present study describes the molecular epidemiology of Human herpesvirus 8 (HHV-8) among four Indian tribes (Kararao, Arara Laranjal, Tiriyo, and Zo'e) of the Amazon region of Brazil and a group of HIV-1-infected subjects from the urban population of Belem, Para. Infection was characterized by the presence of antibodies using ELISA (measuring antibodies to ORF59, ORF65, K8.1A, K8.1B, and ORF73), and molecular assays (gene amplification of the regions ORF26 and the variable region VR1… CONTINUE READING