High dimensional random walks can appear low dimensional: Application to influenza H3N2 evolution.

Abstract

One important feature of the mammalian immune system is the highly specific binding of antigens to antibodies. Antibodies generated in response to one infection may also provide some level of cross immunity to other infections. One model to describe this cross immunity is the notion of antigenic space, which assigns each antibody and each virus a point in… (More)
DOI: 10.1016/j.jtbi.2018.03.022

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