High dietary salt reduces the contribution of 20-HETE to arteriolar oxygen responsiveness in skeletal muscle.

@article{Marvar2007HighDS,
  title={High dietary salt reduces the contribution of 20-HETE to arteriolar oxygen responsiveness in skeletal muscle.},
  author={Paul J. Marvar and John R. Falck and Matthew A. Boegehold},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2007},
  volume={292 3},
  pages={
          H1507-15
        }
}
The coupling of tissue blood flow to cellular metabolic demand involves oxygen-dependent adjustments in arteriolar tone, and arteriolar responses to oxygen can be mediated, in part, by changes in local production of 20-HETE. In this study, we examined the long-term effect of dietary salt on arteriolar oxygen responsiveness in the exteriorized, superfused rat spinotrapezius muscle and the role of 20-HETE in this responsiveness. Rats were fed either a normal-salt (NS, 0.45%) or high-salt (HS, 4… 

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