High diagnostic yield by CSF-PCR for entero- and herpes simplex viruses and TBEV serology in adults with acute aseptic meningitis in Stockholm.

@article{FranzenRohl2008HighDY,
  title={High diagnostic yield by CSF-PCR for entero- and herpes simplex viruses and TBEV serology in adults with acute aseptic meningitis in Stockholm.},
  author={Elisabeth Franzen-Rohl and Kenny Larsson and Eva Skoog and Annika Tiveljung-Lindell and Lena Grillner and Elisabeth Aurelius and Martin Glim{\aa}ker},
  journal={Scandinavian journal of infectious diseases},
  year={2008},
  volume={40 11-12},
  pages={914-21}
}
Acute aseptic meningitis (AAM) affects 10-20/100,000 inhabitants per years in Sweden. Up to the beginning of the 1980s the diagnoses were made by virus isolation and/or determination of viral antibodies in serum. The development of PCR for detection of viruses in CSF samples has increased the sensitivity and diagnostic efficiency considerably. We investigated the aetiology of AAM and the diagnostic efficiency in an adult population in Stockholm, using a limited first-line combination of… CONTINUE READING