High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.

@article{Kwitek2004HighdensityRR,
  title={High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.},
  author={Anne E Kwitek and Jo Gullings-Handley and Jiaming Yu and Danilo C. Carlos and Kimberly Orlebeke and Jeff Nie and Jeffrey Eckert and A. Lemke and Jaime Wendt Andrae and Susan Bromberg and Dean Pasko and Dan Chen and Todd E. Scheetz and Thomas L. Casavant and Marcelo Bento Soares and Val C. Sheffield and Peter J. Tonellato and Howard J. Jacob},
  journal={Genome research},
  year={2004},
  volume={14 4},
  pages={750-7}
}
The laboratory rat is a major model organism for systems biology. To complement the cornucopia of physiological and pharmacological data generated in the rat, a large genomic toolset has been developed, culminating in the release of the rat draft genome sequence. The rat draft sequence used a variety of assembly packages, as well as data from the Radiation Hybrid (RH) map of the rat as part of their validation. As part of the Rat Genome Project, we have been building a high-density RH map to… CONTINUE READING