High density lipoprotein utilization by dispersed rat luteal cells.


Utilization of lipoproteins by cells prepared by collagenase dispersion of ovaries of immature gonadotropin-primed rats was studied. Human and rat HDL increased basal progestin secretion and incorporation of [14C]oleate into cellular sterol esters 2-fold during a 2 h incubation, with maximal stimulation occurring at a lipoprotein sterol concentration of 125… (More)