High-density lipoprotein stimulates myocardial perfusion in vivo.

  title={High-density lipoprotein stimulates myocardial perfusion in vivo.},
  author={Bodo Levkau and Sven Hermann and Gregor Theilmeier and Markus van der Giet and Jerold Chun and Otmar Schober and Michael Sch{\"a}fers},
  volume={110 21},
BACKGROUND Several clinical studies have demonstrated a close association between plasma HDL cholesterol levels and endothelium-dependent vasodilation in peripheral arteries. In isolated arteries, HDL has been shown to mediate vasodilation via NO release. In vivo, administration of reconstituted HDL restored abnormal endothelial function of the brachial artery in hypercholesterolemic patients. However, no data are currently available on the effect of HDL on myocardial perfusion. METHODS AND… CONTINUE READING

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