High-density lipoprotein enhancement of anticoagulant activities of plasma protein S and activated protein C.

@article{Griffin1999HighdensityLE,
  title={High-density lipoprotein enhancement of anticoagulant activities of plasma protein S and activated protein C.},
  author={John H. Griffin and Kazuhisa Kojima and Carole L. Banka and Linda K. Curtiss and Jos{\'e} Aneiros Fern{\'a}ndez},
  journal={The Journal of clinical investigation},
  year={1999},
  volume={103 2},
  pages={
          219-27
        }
}
Low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol levels are associated, respectively, with either increased risk or apparent protective effects for atherothrombosis. The ability of purified LDL and HDL to downregulate thrombin formation, a contributor to atherothrombotic processes, was assessed. Purified HDL, but not LDL, significantly enhanced inactivation of coagulation factor Va by activated protein C (APC) and protein S, and HDL stimulated protein S-dependent… CONTINUE READING

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References

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SHOWING 1-10 OF 66 REFERENCES

Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein

  • J Rosing
  • C. J. Biol
  • 1995
Highly Influential
5 Excerpts

Antiatherogenic effects of high-density lipoproteins: mechanisms

  • Barter, P.J
  • Atherosclerosis XI .
  • 1998

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