High-density lipoprotein and inflammation in cardiovascular disease.

  title={High-density lipoprotein and inflammation in cardiovascular disease.},
  author={Margery A. Connelly and Irina Shalaurova and James D. Otvos},
  journal={Translational research : the journal of laboratory and clinical medicine},
Great advances are being made at the mechanistic level in the understanding of the structural and functional diversity of high-density lipoprotein (HDL). HDL particle subspecies of different sizes are now known to differ in the protein and lipid cargo they transport, conferring on them the ability to perform different functions that in aggregate would be expected to provide protection against the development of atherosclerosis and its downstream clinical consequences. Exacerbating what is… CONTINUE READING
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