High degree of conservancy among secreted salivary gland proteins from two geographically distant Phlebotomus duboscqi sandflies populations (Mali and Kenya)

@article{Kato2006HighDO,
  title={High degree of conservancy among secreted salivary gland proteins from two geographically distant Phlebotomus duboscqi sandflies populations (Mali and Kenya)},
  author={Hirotomo Kato and Jennifer M. Anderson and Shaden Kamhawi and Fabiano Oliveira and Phillip G. Lawyer and Van My Pham and Constance Souko Sangare and Sibiry Samake and Ibrahim Moussa Sissoko and Mark K. Garfield and Lucie Sigutova and Petr Volf and Seydou Doumbia and Jesus G Valenzuela},
  journal={BMC Genomics},
  year={2006},
  volume={7},
  pages={226 - 226}
}
Salivary proteins from sandflies are potential targets for exploitation as vaccines to control Leishmania infection; in this work we tested the hypothesis that salivary proteins from geographically distant Phlebotomus duboscqi sandfly populations are highly divergent due to the pressure exerted by the host immune response. Salivary gland cDNA libraries were prepared from wild-caught P. duboscqi from Mali and recently colonised flies of the same species from Kenya. Transcriptome and proteome… CONTINUE READING

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