High-conductance chloride channels in BC3H1 myoblasts.

  title={High-conductance chloride channels in BC3H1 myoblasts.},
  author={O Hurn{\'a}k and Jozef Zachar},
  journal={General physiology and biophysics},
  volume={12 2},
The existence of a high-conductance voltage sensitive chloride channel in BC3H1 myoblasts is documented. The conductance of the channel in symmetrical 150 mmol/l sodium chloride is around 400 pS. The probability of the channel being in the open state decreases with increasing of the imposed voltage from holding potential (0 mV) in both the depolarizing and the hyperpolarizing direction respectively. The bell-shaped open probability plot is asymmetrical, and can be fitted by two Boltzmann… CONTINUE READING

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