High concordance of gene methylation in post-digital rectal examination and post-biopsy urine samples for prostate cancer detection.

@article{Rogers2006HighCO,
  title={High concordance of gene methylation in post-digital rectal examination and post-biopsy urine samples for prostate cancer detection.},
  author={Craig Rogers and Mark L. Gonzalgo and Gai Yan and Patrick Jan Bastian and David Yuk-Ming Chan and William Andrew Nelson and Christian P Pavlovich},
  journal={The Journal of urology},
  year={2006},
  volume={176 5},
  pages={2280-4}
}
PURPOSE We evaluated the concordance between post-digital rectal examination and post-prostate biopsy urine samples using conventional methylation specific polymerase chain reaction analysis of 3 gene promoters in patients with suspected or confirmed prostate cancer. MATERIALS AND METHODS Voided urine specimens were collected from 17 men after 15-second digital rectal examination and again after transrectal ultrasound guided biopsy of the prostate for suspected malignancy or for followup… CONTINUE READING
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