High-cell-density cultivation of the lipid accumulating yeast Cryptococcus curvatus using glycerol as a carbon source

  title={High-cell-density cultivation of the lipid accumulating yeast Cryptococcus curvatus using glycerol as a carbon source},
  author={P. A. E. P. Meesters and G. N. M. Huijberts and Gerrit Eggink},
  journal={Applied Microbiology and Biotechnology},
 Cryptococcus curvatus is a yeast with industrial potential because it can grow and accumulate lipid on a very broad range of substrates. In this study we describe growth and lipid accumulation on glycerol in a fed-batch fermentation mode. We performed a fermentation consisting of two phases. The first phase is the biomass production phase in which there is no nutrient limitation except for very short periods of glycerol exhaustion. The substrate feed was controlled by the dissolved oxygen… CONTINUE READING
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