High cancer risk and increased mortality in patients with Peutz-Jeghers syndrome.

@article{Lier2011HighCR,
  title={High cancer risk and increased mortality in patients with Peutz-Jeghers syndrome.},
  author={Margot G F van Lier and Anne Marie Westerman and Anja Wagner and Caspar W. N. Looman and John P. Wilson and Felix W. M. de Rooij and Valery E. P. P. Lemmens and Ernst J Kuipers and Elisabeth M. H. Mathus-Vliegen and Monique Esther van Leerdam},
  journal={Gut},
  year={2011},
  volume={60 2},
  pages={141-7}
}
BACKGROUND Peutz-Jeghers syndrome (PJS) is associated with an increased cancer risk. As the determination of optimal surveillance strategies is hampered by wide ranges in cancer risk estimates and lack of data on cancer-related mortality, we assessed cancer risks and mortality in a large cohort of patients with PJS. METHODS Dutch PJS patients were included in this cohort study. Patients were followed prospectively between January 1995 and July 2009, and clinical data from the period before… CONTINUE READING

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