High calcium concentrations shift the mode of exocytosis to the kiss-and-run mechanism

@article{Als1999HighCC,
  title={High calcium concentrations shift the mode of exocytosis to the kiss-and-run mechanism},
  author={Eva Al{\'e}s and L. Tabares and J. Poyato and Vicente Valero and Manfred Lindau and Guillermo Alvarez de Toledo},
  journal={Nature Cell Biology},
  year={1999},
  volume={1},
  pages={40-44}
}
Exocytosis, the fusion of secretory vesicles with the plasma membrane to allow release of the contents of the vesicles into the extracellular environment, and endocytosis, the internalization of these vesicles to allow another round of secretion, are coupled. It is, however, uncertain whether exocytosis and endocytosis are tightly coupled, such that secretory vesicles fuse only transiently with the plasma membrane before being internalized (the ‘kiss-and-run’ mechanism), or whether endocytosis… 
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    Proceedings of the National Academy of Sciences of the United States of America
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