High bone marrow angiopoietin-1 expression is an independent poor prognostic factor for survival in patients with myelodysplastic syndromes

@inproceedings{Cheng2011HighBM,
  title={High bone marrow angiopoietin-1 expression is an independent poor prognostic factor for survival in patients with myelodysplastic syndromes},
  author={C Cheng and H A Hou and J-Y Jhuang and C. P. Lin and C. T. A. Chen and J Tang and W-C Chou and M-H Tseng and Ming Yao and S P Huang and B-S Ko and S C Hsu and Shin-Jye Wu and Woei Tsay and Yee-Chun Chen and H -F Tien},
  booktitle={British Journal of Cancer},
  year={2011}
}
Background:Angiogenic factors have an essential role in normal and pathologic angiogenesis. However, the clinical implication of angiogenic factor expression in myelodysplastic syndromes (MDS) remains unclear.Methods:In this study, we sought to investigate the prognostic impact of the expression of genes encoding angiopoietin-1 (Ang-1), Ang-2, the receptor Tie2, vascular endothelial growth factor-A (VEGF-A) and VEGF-C in the bone marrow (BM) in 208 patients with newly diagnosed primary MDS… CONTINUE READING
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