High antibody response to autologous type II collagen is restricted to H-2 q

@article{Holmdahl1986HighAR,
  title={High antibody response to autologous type II collagen is restricted to H-2 q},
  author={Rikard Holmdahl and Lars Klareskog and Mikael Svante Andersson and Carl Hansen},
  journal={Immunogenetics},
  year={1986},
  volume={24},
  pages={84-89}
}
The incidence of arthritis and the antibody response to mouse and to rat type 11 collagen after immunization with native rat type II collagen was studied in different mouse strains, including wild mouse-derived strains belonging to the H-2p/H-2q family. High serum levels of antibodies to mouse and rat type II collagen were seen only in H-2q mice, whereas mice belonging to the p, w3, w5, and w17 haplotypes displayed low type II collagen-specific antibody responses. Mice from three different H-2q… CONTINUE READING
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A rapid and efficient immunization protocol for production ofmonoclonal antibodies reactive with autoantigens

  • R. Hohndahl, T. Moran, M. Andersson
  • J. Immunol. Methods
  • 1985

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