High- and low-mobility populations of HP1 in heterochromatin of mammalian cells.

@article{Schmiedeberg2004HighAL,
  title={High- and low-mobility populations of HP1 in heterochromatin of mammalian cells.},
  author={Lars Schmiedeberg and Klaus Weisshart and Stephan Diekmann and Gabriele Meyer Zu Hoerste and Peter H. Hemmerich},
  journal={Molecular biology of the cell},
  year={2004},
  volume={15 6},
  pages={
          2819-33
        }
}
Heterochromatin protein 1 (HP1) is a conserved nonhistone chromosomal protein with functions in euchromatin and heterochromatin. Here we investigated the diffusional behaviors of HP1 isoforms in mammalian cells. Using fluorescence correlation spectroscopy (FCS) and fluorescence recovery after photobleaching (FRAP) we found that in interphase cells most HP1… CONTINUE READING