High-altitude pulmonary edema is initially caused by an increase in capillary pressure.

@article{Maggiorini2001HighaltitudePE,
  title={High-altitude pulmonary edema is initially caused by an increase in capillary pressure.},
  author={Marco Maggiorini and Christian M{\'e}lot and Saulnier Pierre and Fr{\'e}d{\'e}rique Pfeiffer and I Mauduyt de la Gr{\`e}ve and Claudio Sartori and M. Lepori and Michael Hauser and Urs Scherrer and Robert Naeije},
  journal={Circulation},
  year={2001},
  volume={103 16},
  pages={2078-83}
}
BACKGROUND High-altitude pulmonary edema (HAPE) is characterized by severe pulmonary hypertension and bronchoalveolar lavage fluid changes indicative of inflammation. It is not known, however, whether the primary event is an increase in pressure or an increase in permeability of the pulmonary capillaries. METHODS AND RESULTS We studied pulmonary hemodynamics, including capillary pressure determined by the occlusion method, and capillary permeability evaluated by the pulmonary transvascular… CONTINUE READING
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