High altitude and free radicals.

  title={High altitude and free radicals.},
  author={Tibor Bakonyi and Zsolt Rad{\'a}k},
  journal={Journal of sports science & medicine},
  volume={3 2},
High altitude exposure results in decreased oxygen pressure and an increased formation of reactive oxygen and nitrogen species (RONS), which is often associated with increases in oxidative damage to lipids, proteins and DNA. Exposure to high altitude appears to decrease the activity and effectiveness of antioxidant enzymes system. Moreover, during high altitude exposure several RONS generating source are activated, including mitochondrial electron transport chain, xanthine oxidase, and nitric… CONTINUE READING