High-affinity growth hormone (GH)-binding protein (GHBP), body fat mass, and insulin-like growth factor-binding protein-3 predict the GHBP response to GH therapy in adult GH deficiency syndrome.

@article{Roelen1999HighaffinityGH,
  title={High-affinity growth hormone (GH)-binding protein (GHBP), body fat mass, and insulin-like growth factor-binding protein-3 predict the GHBP response to GH therapy in adult GH deficiency syndrome.},
  author={Corn{\'e} A M Roelen and H. P. F. Koppeschaar and Wouter R. De Vries and M. E. Doerga and Y. E. M. Snel and Eduard Bol and Pierre M. J. Zelissen and Joseph Helenus Hubert Thijssen and Marinus A. Blankenstein},
  journal={Metabolism: clinical and experimental},
  year={1999},
  volume={48 3},
  pages={
          314-8
        }
}
The study objective was to investigate which baseline factors can accurately predict plasma high-affinity growth hormone (GH)-binding protein (GHBP) levels after GH replacement therapy in patients with GH deficiency (GHD). The study group consisted of 36 GHD patients (22 men and 14 women; mean age, 43.1 years; (range, 21 to 60) known to have adult-onset GHD for many years (range, 4 to 22). They were randomly divided into a GH-treated group (n = 19) and a placebo group (n = 17). Body composition… CONTINUE READING
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