High-abundance polypeptides of the human plasma proteome comprising the top 4 logs of polypeptide abundance.

@article{Hortin2008HighabundancePO,
  title={High-abundance polypeptides of the human plasma proteome comprising the top 4 logs of polypeptide abundance.},
  author={Glen L. Hortin and Denis Sviridov and Nathaniel Anderson},
  journal={Clinical chemistry},
  year={2008},
  volume={54 10},
  pages={1608-16}
}
BACKGROUND Plasma contains thousands of proteins, but a small number of these proteins comprise the majority of protein molecules and mass. CONTENT We surveyed proteomic studies to identify candidates for high-abundance polypeptide chains. We searched the literature for information on the plasma concentrations of the most abundant components in healthy adults and for the molecular mass of the mature polypeptide chains in plasma. Because proteomic studies usually dissociate proteins into… CONTINUE READING

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