High Throughput Measurement of Extracellular DNA Release and Quantitative NET Formation in Human Neutrophils In Vitro.

Abstract

Neutrophil granulocytes are the most abundant leukocytes in the human blood. Neutrophils are the first to arrive at the site of infection. Neutrophils developed several antimicrobial mechanisms including phagocytosis, degranulation and formation of neutrophil extracellular traps (NETs). NETs consist of a DNA scaffold decorated with histones and several… (More)
DOI: 10.3791/52779

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@article{Sil2016HighTM, title={High Throughput Measurement of Extracellular DNA Release and Quantitative NET Formation in Human Neutrophils In Vitro.}, author={Payel Sil and Dae-goon Yoo and Madison Floyd and Aaron D Gingerich and Bal{\'a}zs Rada}, journal={Journal of visualized experiments : JoVE}, year={2016}, volume={112} }