High TUG1 expression is associated with chemotherapy resistance and poor prognosis in esophageal squamous cell carcinoma

@article{Jiang2016HighTE,
  title={High TUG1 expression is associated with chemotherapy resistance and poor prognosis in esophageal squamous cell carcinoma},
  author={Lin Jiang and Wenchao Wang and Guoli Li and Canlin Sun and Zhenqin Ren and Haihui Sheng and Hengjun Gao and Chaofu Wang and Hong Yu},
  journal={Cancer Chemotherapy and Pharmacology},
  year={2016},
  volume={78},
  pages={333-339}
}
PurposeLong noncoding RNAs (lncRNAs) play critical roles in diverse biological processes such as tumorigenesis and metastasis. Taurine upregulated gene 1 (TUG1) is a cancer-related lncRNA that is associated with chromatin-modifying complexes and plays an important role in gene regulation. In this study, we determined the expression patterns of TUG1 in esophageal squamous cell carcinoma (ESCC) and evaluated its clinical significance.MethodsThe expression level of TUG1 was examined in 218 pairs… CONTINUE READING

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