High Resolution Intravital Imaging of Subcellular Structures of Mouse Abdominal Organs Using a Microstage Device

@inproceedings{Cao2012HighRI,
  title={High Resolution Intravital Imaging of Subcellular Structures of Mouse Abdominal Organs Using a Microstage Device},
  author={Liqin Cao and Satoru Kobayakawa and Atsushi Yoshiki and Kuniya Abe},
  booktitle={PloS one},
  year={2012}
}
Intravital imaging of brain and bone marrow cells in the skull with subcellular resolution has revolutionized neurobiology, immunology and hematology. However, the application of this powerful technology in studies of abdominal organs has long been impeded by organ motion caused by breathing and heartbeat. Here we describe for the first time a simple device designated 'microstage' that effectively reduces organ motions without causing tissue lesions. Combining this microstage device with an… CONTINUE READING