High Performance computing improvements on bioinformatics consistency-based multiple sequence alignment tools

@article{Orobitg2015HighPC,
  title={High Performance computing improvements on bioinformatics consistency-based multiple sequence alignment tools},
  author={Miquel Orobitg and Fernando Guirado and Fernando Cores and Jordi Llad{\'o}s and C{\'e}dric Notredame},
  journal={Parallel Computing},
  year={2015},
  volume={42},
  pages={18-34}
}
Multiple Sequence Alignment (MSA) is essential for a wide range of applications in Bioinformatics. Traditionally, the alignment accuracy was the main metric used to evaluate the goodness of MSA tools. However, with the growth of sequencing data, other features, such as performance and the capacity to align larger datasets, are gaining strength. To achieve these new requirements, without affecting accuracy, the use of high-performance computing (HPC) resources and techniques is crucial. In this… CONTINUE READING

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