High-Performance Liquid Chromatography (HPLC) Quantification of Liposome-Delivered Doxorubicin in Arthritic Joints of Collagen-Induced Arthritis Rats

Abstract

BACKGROUND Neoangiogenesis occurring in inflamed articular synovium in early rheumatoid arthritis (RA) is characterized by enhanced vascular permeability that allows nanoparticle agents, including liposomes, to deliver encapsulated drugs to arthritic joints and subsequently improve therapeutic efficacy and reduce adverse effects. However, the targeting… (More)

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@inproceedings{Niu2017HighPerformanceLC, title={High-Performance Liquid Chromatography (HPLC) Quantification of Liposome-Delivered Doxorubicin in Arthritic Joints of Collagen-Induced Arthritis Rats}, author={Hongqing Niu and Menghua Xu and Shuangtian Li and Junwei Chen and Jing Luo and Xiangcong Zhao and Chong Gao and Xiaofeng Li}, booktitle={Medical science monitor basic research}, year={2017} }