High NRF2 expression controls endoplasmic reticulum stress induced apoptosis in multiple myeloma.

Abstract

Multiple myeloma (MM) is an incurable disease characterized by clonal plasma cell proliferation. The stress response transcription factor Nuclear factor erythroid 2 [NF-E2]-related factor 2 (NRF2) is known to be activated in MM in response to proteasome inhibitors (PI). Here, we hypothesize that the transcription factor NRF2 whose physiological role is to… (More)
DOI: 10.1016/j.canlet.2017.10.005

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Cite this paper

@article{Sun2018HighNE, title={High NRF2 expression controls endoplasmic reticulum stress induced apoptosis in multiple myeloma.}, author={Yu Sun and Amina Abdul Aziz and Kristian M. Bowles and Stuart A. Rushworth}, journal={Cancer letters}, year={2018}, volume={412}, pages={37-45} }