High Molecular Weight Pro-Sucrase-Isomaltase in Human Fetal Intestine

  title={High Molecular Weight Pro-Sucrase-Isomaltase in Human Fetal Intestine},
  author={Hanne Skovbjerg},
  journal={Pediatric Research},
Summary: Sucrase-isomaltase (SI) was isolated by immunoprecipitation from the intestines of human fetuses of 16–20 wk of gestational age as one large polypeptide (pro-SI) with a molecular weight of 260,000. Treatment with elastase converted the pro-SI into two polypeptides of apparent molecular weights as sucrase and isomaltase from normal adult intestine (Mr 140,000 and 150,000, respectively). The pro-SI had full enzymatic activity.Speculation: The results indicate that human sucrase… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 13 references

Human fetal intestinal brush border sucrase , oligoaminopeptidase and dipeptidylaminopeptidase

  • S. Auricchio, C Caporale, F. Santamaria.
  • Pediatr . Res . , /
  • 1981

Intestinal oligo - and disaccharidases

  • G. Semenza
  • 1981

Intrauterine development of gastrointestinal tract function

  • R. E. Kimura, B. Warshaw.J.
  • E . Lebenthal : Textbook of Gastroenterology and…
  • 1981

A rapid and sensitive method for the quanti tat ion of microgram quantities of protein utilizing the principle of protein - dye binding

  • M. M. Bradford
  • Anal . Biochem .
  • 1976

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