High LIN28A Expressing Ovarian Cancer Cells Secrete Exosomes That Induce Invasion and Migration in HEK293 Cells

@inproceedings{Enriquez2015HighLE,
  title={High LIN28A Expressing Ovarian Cancer Cells Secrete Exosomes That Induce Invasion and Migration in HEK293 Cells},
  author={Vanessa A. Enriquez and Ellane R. Cleys and Juliano C da Silveira and Monique A. Spillman and Quinton A. Winger and Gerrit J. Bouma},
  booktitle={BioMed research international},
  year={2015}
}
Epithelial ovarian cancer is the most aggressive and deadly form of ovarian cancer and is the most lethal gynecological malignancy worldwide; therefore, efforts to elucidate the molecular factors that lead to epithelial ovarian cancer are essential to better understand this disease. Recent studies reveal that tumor cells release cell-secreted vesicles called exosomes and these exosomes can transfer RNAs and miRNAs to distant sites, leading to cell transformation and tumor development. The RNA… CONTINUE READING

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 52 references

Similar Papers

Loading similar papers…