High Ki67, Bax, and thymidylate synthase expression well correlates with response to chemoradiation therapy in locally advanced rectal cancers: proposal of a logistic model for prediction

@article{Kikuchi2009HighKB,
  title={High Ki67, Bax, and thymidylate synthase expression well correlates with response to chemoradiation therapy in locally advanced rectal cancers: proposal of a logistic model for prediction},
  author={Masanori Kikuchi and Tetuo Mikami and Tadakazu Sato and Wataru Tokuyama and Keijiro Araki and Michiaki Watanabe and Katunori Saigenji and Isao Okayasu},
  journal={British Journal of Cancer},
  year={2009},
  volume={101},
  pages={116 - 123}
}
Background:Recently, preoperative chemoradiation therapy (CRT) for rectal cancer has been increasingly used as a neoadjuvant treatment. In the present study, the relation between histological response to CRT and immunohistochemical markers in biopsy specimens was investigated.Methods:Biopsy specimens from a total of 60 patients were collected before preoperative CRT with S-1 and irinotecan, and liniac 45 Gy. Immunohistochemical staining for Ki67, Mcm3, Bax, Bcl-2, ssDNA, Grp78, thymidylate… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 34 CITATIONS

unica granatum suppresses colon cancer through downregulation of nt /-Catenin in rat model anaa

H. Ahmeda, Hanan S. El-Abharb, Elsayed Abdul Khalik Hassaninc, Noha F. Abdelkaderb, B. Shalabyc
  • 2017
VIEW 2 EXCERPTS
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 52 REFERENCES