High Ki-67 expression in diffuse large B-cell lymphoma patients with non-germinal center subtype indicates limited survival benefit from R-CHOP therapy.

@article{Li2012HighKE,
  title={High Ki-67 expression in diffuse large B-cell lymphoma patients with non-germinal center subtype indicates limited survival benefit from R-CHOP therapy.},
  author={Zhi-Ming Li and Jia-jia Huang and Y S Xia and Ying-Jie Zhu and Wei Zhao and Wen-Xiao Wei and Wenqi Jiang and Tongyu Lin and Hui-qiang Huang and Zhong-zhen Guan},
  journal={European journal of haematology},
  year={2012},
  volume={88 6},
  pages={510-7}
}
OBJECTIVES Rituximab has significantly improved the survival of patients with DLBCL, especially those with non-germinal center B-cell-like (non-GCB) subtype. The impact of Ki-67 expression, an index of proliferation, on the clinical outcomes of patients with DLBCL has largely been unexplored. This study aimed to investigate whether Ki-67 expression is an indicator of outcome in DLBCL patients (especially non-GCB DLBCL patients) treated with standard chemotherapy combined with rituximab… CONTINUE READING

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