High Intrinsic Aerobic Capacity Protects against Ethanol-Induced Hepatic Injury and Metabolic Dysfunction: Study Using High Capacity Runner Rat Model.

@article{Szary2015HighIA,
  title={High Intrinsic Aerobic Capacity Protects against Ethanol-Induced Hepatic Injury and Metabolic Dysfunction: Study Using High Capacity Runner Rat Model.},
  author={Nicholas M Szary and Randy Scott Rector and Grace M. E. Uptergrove and Suzanne E. Ridenhour and Shivendra D. Shukla and John P Thyfault and Lauren Gerard Koch and Steven Loyal Britton and Jamal A Ibdah},
  journal={Biomolecules},
  year={2015},
  volume={5 4},
  pages={3295-308}
}
Rats artificially selected over several generations for high intrinsic endurance/aerobic capacity resulting in high capacity runners (HCR) has been developed to study the links between high aerobic fitness and protection from metabolic diseases (Wisloff et al., Science, 2005). We have previously shown that the HCR strain have elevated hepatic mitochondrial… CONTINUE READING