High HSF4 expression is an independent indicator of poor overall survival and recurrence free survival in patients with primary colorectal cancer.

@article{Yang2017HighHE,
  title={High HSF4 expression is an independent indicator of poor overall survival and recurrence free survival in patients with primary colorectal cancer.},
  author={Yingchi Yang and Lan Shu Jin and Jinghui Zhang and Jin Wang and Xiaomu Zhao and Guocong Wu and Hongwei Yao and Zhongtao Zhang},
  journal={IUBMB life},
  year={2017},
  volume={69 12},
  pages={
          956-961
        }
}
Heat shock factor 4 (HSF4) is a member of the HSF family. In this study, by using data from the Cancer Genome Atlas-Colorectal Cancer (TCGA-CRC), we investigated the expression profile and the prognostic value of the HSF4 in terms of overall survival (OS) and recurrence free survival (RFS) in CRC patients. RNA-Seq data showed that HSF4 RNA expression was significantly higher in CRC tissues (N = 380) than in the corresponding normal tissues (N = 51) (mean ± SD: 3.56 ± 1.28 vs. 1.85 ± 0.87, P < 0… CONTINUE READING
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