High HIV-1 genetic diversity in Cuba

@article{Cuevas2002HighHG,
  title={High HIV-1 genetic diversity in Cuba},
  author={Mar{\'i}a Teresa Cuevas and Ignacio Ruibal and Mar{\'i}a Luisa Villahermosa and H{\'e}ctor M. D{\'i}az and Elena Delgado and Elena V{\'a}zquez-de Parga and Luc{\'i}a P{\'e}rez-{\'A}lvarez and Madeline Blanco de Armas and Laureano Cuevas and Leandro Medrano and Enrique Noa and Saladin Osmanov and Rafael N{\'a}jera and Michael M. Thomson},
  journal={AIDS},
  year={2002},
  volume={16},
  pages={1643-1653}
}
BackgroundHIV-1 subtype B is largely predominant in the Caribbean, although other subtypes have been recently identified in Cuba. ObjectivesTo examine HIV-1 genetic diversity in Cuba. MethodsThe study enrolled 105 HIV-1-infected individuals, 93 of whom had acquired the infection in Cuba. DNA from peripheral blood mononuclear cells was used for polymerase chain reaction amplification and sequencing of pol (protease–reverse transcriptase) and env (V3 region) segments. Phylogenetic trees were… Expand
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