High-Grade Acute Organ Toxicity as Positive Prognostic Factor in Primary Radio(chemo)therapy for Locally Advanced, Inoperable Head and Neck Cancer

@article{Wolff2010HighGradeAO,
  title={High-Grade Acute Organ Toxicity as Positive Prognostic Factor in Primary Radio(chemo)therapy for Locally Advanced, Inoperable Head and Neck Cancer},
  author={Hendrik Andreas Wolff and Jan Bosch and Klaus Jung and Tobias R. Overbeck and Steffen Hennies and Christoph Matthias and Clemens Friedrich Hess and Ralph M. W. R{\"o}del and P H Christiansen},
  journal={Strahlentherapie und Onkologie},
  year={2010},
  volume={186},
  pages={262-268}
}
To test for a possible correlation between high-grade acute organ toxicity during primary radio(chemo)therapy and treatment outcome in patients with locally advanced head and neck squamous cell carcinoma (HNSCC). From 05/1994 to 01/2009, 216 HNSCC patients were treated with radio(chemo)therapy in primary approach. They received normofractionated (2 Gy/fraction) irradiation including associated nodal drainage sites to a cumulative dose of 70 Gy. 151 patients received additional concomitant… CONTINUE READING
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