High Fat Diet Induces Liver Steatosis and Early Dysregulation of Iron Metabolism in Rats

@inproceedings{Meli2013HighFD,
  title={High Fat Diet Induces Liver Steatosis and Early Dysregulation of Iron Metabolism in Rats},
  author={Rosaria Meli and Giuseppina Mattace Raso and Carlo Irace and Raffaele Simeoli and Antonio Di Pascale and Orlando Paciello and Teresa Bruna Pagano and Antonio Calignano and Alfredo Colonna and R. Vila Santamaria},
  booktitle={PloS one},
  year={2013}
}
This paper is dedicated to the memory of our wonderful colleague Professor Alfredo Colonna, who passed away the same day of its acceptance. Fatty liver accumulation, inflammatory process and insulin resistance appear to be crucial in non-alcoholic fatty liver disease (NAFLD), nevertheless emerging findings pointed an important role also for iron overload. Here, we investigate the molecular mechanisms of hepatic iron metabolism in the onset of steatosis to understand whether its impairment could… CONTINUE READING
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