High Expression of Somatostatin Receptor Subtype 2 (sst2) in Medulloblastoma: Implications for Diagnosis and Therapy

@article{Frhwald1999HighEO,
  title={High Expression of Somatostatin Receptor Subtype 2 (sst2) in Medulloblastoma: Implications for Diagnosis and Therapy},
  author={Michael Christoph Fr{\"u}hwald and M. Sue O'dorisio and Torsten Pietsch and Jean Claude Reubi},
  journal={Pediatric Research},
  year={1999},
  volume={45},
  pages={697-708}
}
Medulloblastoma is a pediatric malignancy, which arises in cerebellum. The neuropeptide somatostatin (SS-14) is a neuromodulator and growth regulator in the developing cerebellum. SS-14 has previously been demonstrated in medulloblastomas with immunohistochemical techniques, but somatostatin receptor (sst) expression is less well understood. We analyzed somatostatin and sst subtype expression (sst1-5) in central primitive neuroectodermal tumors (cPNET), including 23 medulloblastomas, 6… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 15 references

Cytogenesis and differentiation of primitive central neuroepithelial tumors

  • I J.
  • J. Neurop t h o l . Exp . Neurol
  • 1972

Intracranial T u mors of Infants and Children

  • W. T. Koos, M. H. Miller
  • Stuttgart, Georg Thienie Verlag,
  • 1971

The Pathology of Tumors of Children

  • R. A. Willis
  • 1962

Similar Papers

Loading similar papers…