High Efficiency Lipid-Based siRNA Transfection of Adipocytes in Suspension

Abstract

BACKGROUND Fully differentiated adipocytes are considered to be refractory to introduction of siRNA via lipid-based transfection. However, large scale siRNA-based loss-of-function screening of adipocytes using either electroporation or virally-mediated transfection approaches can be prohibitively complex and expensive. METHODOLOGY/PRINCIPAL FINDINGS We… (More)
DOI: 10.1371/journal.pone.0006940

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@inproceedings{Kilroy2009HighEL, title={High Efficiency Lipid-Based siRNA Transfection of Adipocytes in Suspension}, author={Gail E. Kilroy and David H. Burk and Z. Elizabeth Floyd}, booktitle={PloS one}, year={2009} }