High-Dose Pyridoxine and Magnesium Administration in Children with Autistic Disorder: An Absence of Salutary Effects in a Double-Blind, Placebo-Controlled Study

@article{Findling1997HighDosePA,
  title={High-Dose Pyridoxine and Magnesium Administration in Children with Autistic Disorder: An Absence of Salutary Effects in a Double-Blind, Placebo-Controlled Study},
  author={R. Findling and K. Maxwell and Lynette Scotese-Wojtila and J. Huang and T. Yamashita and M. Wiznitzer},
  journal={Journal of Autism and Developmental Disorders},
  year={1997},
  volume={27},
  pages={467-478}
}
  • R. Findling, K. Maxwell, +3 authors M. Wiznitzer
  • Published 1997
  • Psychology, Medicine
  • Journal of Autism and Developmental Disorders
  • Several reports have described salutary effects such as decreased physical aggression and improved social responsiveness being associated with the administration of high doses of pyridoxine and magnesium (HDPM) in open-labeled and controlled studies of patients with autism. Despite this fact, this intervention remains controversial. A 10-week double-blind, placebo-controlled trial was undertaken to examine both the efficacy and safety of HDPM in autism. Twelve patients were enrolled, and 10… CONTINUE READING

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