High-Content Screening for Quantitative Cell Biology.

@article{Uaj2016HighContentSF,
  title={High-Content Screening for Quantitative Cell Biology.},
  author={Mojca Mattiazzi U{\vs}aj and Erin Broadley Styles and Adrian J. Verster and Helena Friesen and Charles Boone and Brenda J. Andrews},
  journal={Trends in cell biology},
  year={2016},
  volume={26 8},
  pages={
          598-611
        }
}
High-content screening (HCS), which combines automated fluorescence microscopy with quantitative image analysis, allows the acquisition of unbiased multiparametric data at the single cell level. This approach has been used to address diverse biological questions and identify a plethora of quantitative phenotypes of varying complexity in numerous different model systems. Here, we describe some recent applications of HCS, ranging from the identification of genes required for specific biological… CONTINUE READING
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High-throughput analysis of yeast replicative aging using a microfluidic system.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2015
VIEW 1 EXCERPT

imaging and automated analysis

S. H. Sternberg, J. A. Doudna
  • 2015

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