High‐precision iRT prediction in the targeted analysis of data‐independent acquisition and its impact on identification and quantitation

@inproceedings{Bruderer2016HighprecisionIP,
  title={High‐precision iRT prediction in the targeted analysis of data‐independent acquisition and its impact on identification and quantitation},
  author={Roland Bruderer and Oliver Martin Bernhardt and T. Gandhi and Lukas Reiter},
  booktitle={Proteomics},
  year={2016}
}
Targeted analysis of data-independent acquisition (DIA) data is a powerful mass spectrometric approach for comprehensive, reproducible and precise proteome quantitation. It requires a spectral library, which contains for all considered peptide precursor ions empirically determined fragment ion intensities and their predicted retention time (RT). RTs, however, are not comparable on an absolute scale, especially if heterogeneous measurements are combined. Here, we present a method for high… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 4 times over the past 90 days. VIEW TWEETS
5 Citations
35 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Identification of a set of conserved eukaryotic internal retention time standards for data-independent acquisition mass spectrometry

  • S. J. Parker, H. Roest, G. Rosenberger, Collins, C B.
  • Mol. Cell. Proteomics 2015,
  • 2015
2 Excerpts

Similar Papers

Loading similar papers…