High‐dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centre

  title={High‐dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centre},
  author={C. Boehnke and U. Reuter and U. Flach and S. Schuh-Hofer and K. Einh{\"a}upl and G. Arnold},
  journal={European Journal of Neurology},
  • C. Boehnke, U. Reuter, +3 authors G. Arnold
  • Published 2004
  • Medicine
  • European Journal of Neurology
  • The aim of this study was to investigate the efficacy of riboflavin for the prevention of migraine. An open label study was performed in a specialized outpatient clinic. Patients received 400 mg riboflavin capsules per day. Headache frequency, duration, intensity and the use of abortive drugs were recorded at baseline and 3 and 6 months after treatment. Headache frequency was significantly reduced from 4 days/month at baseline to 2 days/month after 3 and 6 months (P < 0.05). The use of abortive… CONTINUE READING
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