High‐dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centre

@article{Boehnke2004HighdoseRT,
  title={High‐dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centre},
  author={C. Boehnke and U. Reuter and U. Flach and S. Schuh-Hofer and K. Einh{\"a}upl and G. Arnold},
  journal={European Journal of Neurology},
  year={2004},
  volume={11}
}
The aim of this study was to investigate the efficacy of riboflavin for the prevention of migraine. An open label study was performed in a specialized outpatient clinic. Patients received 400 mg riboflavin capsules per day. Headache frequency, duration, intensity and the use of abortive drugs were recorded at baseline and 3 and 6 months after treatment. Headache frequency was significantly reduced from 4 days/month at baseline to 2 days/month after 3 and 6 months (P < 0.05). The use of abortive… Expand
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Because of its high efficacy, excellent tolerability, and low cost, riboflavin is an interesting option for migraine prophylaxis and a candidate for a comparative trial with an established prophyllactic drug. Expand
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Effectiveness of high-dose riboflavin in migraine prophylaxis.
To the Editor: I read with interest the report by Schoenen et al. on high-dose riboflavin for migraine prophylaxis.1 Although the study was designed as a double-blind randomized controlled trial,Expand
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