Hierarchical self-assembly of a coiled-coil peptide into fractal structure.

  title={Hierarchical self-assembly of a coiled-coil peptide into fractal structure.},
  author={Andrea Lomander and Wonmuk Hwang and Shuguang Zhang},
  journal={Nano letters},
  volume={5 7},
Here we report the hierarchical self-assembly of a cross-linkable coiled-coil peptide containing an internal cysteine. Atomic force microscopy (AFM) experiments revealed the fractal structure of the assemblies, and molecular simulations showed that the peptides cross-linked to form clusters of coiled-coils, which further assembled to form globules of tens of nanometers in diameter. Such hierarchical organization was modulated by pH or thiol-reducing agent. Exploitation of the fractal structures… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.


Publications referenced by this paper.

Fractals and Chaos

B. Mandelbrot
The Mandelbrot Set and Beyond • 2004